BIOCHEMISTRY

A CRITICAL EXAMINATION OF AUTOIMMUNITY AND INFLAMMATION

A CRITICAL EXAMINATION OF AUTOIMMUNITY AND INFLAMMATION

ABSTRACT

When our body encounters something foreign in its environment it needs to be able to mount an immune response against that substance to protect itself from potential harm. In order to do this effectively it must be able to recognize what is self in order to respond to non-self or foreign. In autoimmune disease there is a failure to recognize some part of self, with potential serious consequence Autoimmune disease disorders and its usually accompanying symptom, inflammation result in destruction of one or more types of body tissues abnormal growth of an organ, or changes in organ function. The disorder may affect only one organ or tissue type or many affect multiple organ and tissue. Organs and tissues, commonly affected include blood components such as red blood cells, blood vessels, connective tissue, endocrine glands such as the thyroid or pancreas, muscles, joints and skin.

TABLE OF CONTENTS

TITLE PAGE I
ABSTRACT II
TABLE OF CONTENT III

CHAPTER ONE
1.0 INTRODUCTION 1
1.1 AUTOIMMUNITY 1
1.1.1 TYPES OF AUTO IMMUNITY 5
1.2 INFLAMMATION 9
1.3 HEALTH BENEFITS OF INFLAMMATION 10

CHAPTER TWO
2.0 PATHOGENESIS AND TREATMENT OF
AUTOIMMUNITY 14
2.1 PATHOGENESIS 14
2.1.1 GENETIC FACTORS 14
2.1.2 ENVIRONMENTAL FACTORS 15
2.1.3 OTHER FACTORS 16
2.2 PEOPLE AT RISK FOR AUTOIMMUNE DISEASE 19
2.3 DIAGNOSIS 20
2.4 TREATMENT OF AUTOIMMUNITY 21

CHAPTER THREE
3.0 DESCRIPTION OF INFLAMMATION AND ITS
RELATIONSHIP WITH AUTOIMMUNITY 25
3.1 TYPES OF INFLAMMATION 25
3.2 REACTION MECHANISMS OF INFLAMMATION 27
3.3 POSSIBLE TREATMENTS FOR INFLAMMATION 40
3.4 AUTOIMMUNE DISORDERS AND INFLAMMATION 43

CHAPTER FOUR
4.0 CONCLUSION AND RECOMMENDATIONS 46
4.1 CONCLUSION 46
4.2 RECOMMENDATIONS 47

REFERENCES 48.